Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging-Reference-Cited by-同舟云学术

Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging

Published:2021-07-23 Issue:30 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Adori Csaba¹^ORCID,Daraio Teresa²,Kuiper Raoul³,Barde Swapnali¹^ORCID,Horvathova Lubica⁴^ORCID,Yoshitake Takashi⁵^ORCID,Ihnatko Robert⁶^ORCID,Valladolid-Acebes Ismael²^ORCID,Vercruysse Pauline²,Wellendorf Ashley M.⁷,Gramignoli Roberto³^ORCID,Bozoky Bela⁸,Kehr Jan⁵,Theodorsson Elvar⁶^ORCID,Cancelas Jose A.⁷⁹,Mravec Boris⁴¹⁰^ORCID,Jorns Carl¹¹^ORCID,Ellis Ewa¹²^ORCID,Mulder Jan¹^ORCID,Uhlén Mathias¹¹³^ORCID,Bark Christina¹^ORCID,Hökfelt Tomas¹

Affiliation:

1. Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.

2. The Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, 17176 Stockholm, Sweden.

3. Department of Laboratory Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.

4. Biomedical Research Center, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovak Republic.

5. Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden.

6. Department of Clinical Chemistry and Department of Clinical and Experimental Medicine, Linköping University, 58285 Linköping, Sweden.

7. Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229-3039, USA.

8. Department of Clinical Pathology/Cytology, Karolinska University Hospital, Huddinge, Sweden.

9. Hoxworth Blood Center, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0055, USA.

10. Institute of Physiology, Faculty of Medicine, Comenius University in Bratislava, Slovak Republic.

11. PO Transplantation, Karolinska University Hospital Huddinge, 141 52 Stockholm, Sweden.

12. Department of Transplantation Surgery and Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska University Hospital, Karolinska Institutet, 17177 Stockholm, Sweden.

13. Science for Life Laboratory, Royal Institute of Technology, 10691 Stockholm, Sweden.

Abstract

3D imaging reveals gradual degeneration of liver sympathetic nerves in human and experimental nonalcoholic fatty liver disease.

Funder

Swedish Research Council Formas

Knut and Alice Wallenberg foundation

Åhlén-Foundation

Sven Mattsson’s Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary