The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation-Reference-Cited by-同舟云学术

The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation

Published:2019-03 Issue:3 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Jin Xi¹²³^ORCID,Xu Xiao-En¹²³⁴^ORCID,Jiang Yi-Zhou¹²³⁴^ORCID,Liu Yi-Rong¹²³,Sun Wei¹²³,Guo Ya-Jie¹²³,Ren Yi-Xing¹²³,Zuo Wen-Jia¹²³⁴,Hu Xin¹²³⁴,Huang Sheng-Lin³⁴⁵,Shen Hong-Jie⁶,Lan Fei⁶,He Yun-Fei⁷,Hu Guo-Hong⁷^ORCID,Di Gen-Hong¹²³⁴,He Xiang-Huo³⁴⁵^ORCID,Li Da-Qiang³⁴⁵^ORCID,Liu Suling¹²⁵^ORCID,Yu Ke-Da¹²³⁴^ORCID,Shao Zhi-Ming¹²³⁴^ORCID

Affiliation:

1. Department of Breast Surgery, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai 200032, P. R. China.

2. Cancer Institute, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai 200032, P. R. China.

3. Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong-An Road, Shanghai 200032, P. R. China.

4. Precision Cancer Medicine Center, Fudan University Shanghai Cancer Center, 270 Dong-An Road, Shanghai 200032, P. R. China.

5. Institutes of Biomedical Sciences, Fudan University, Shanghai, P. R. China.

6. Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, and Key Laboratory of Epigenetics, Department of Cellular and Genetic Medicine, School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P. R. China.

7. The Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P. R. China.

Abstract

HERV loci transcribed lncRNA TROJAN promotes TNBC progression through ZMYND8 degradation by the ubiquitin-proteasome pathway.

Funder

National Natural Science Foundation of China

the National Natural Science Foundation of China

Shanghai Pujiang Program

the Municipal Project for Developing Emerging and Frontier Technology in Shanghai Hospitals

the Cooperation Project of Conquering Major Diseases in the Shanghai Municipality Health System

the Innovation Team of the Ministry of Education

the Shanghai Key Laboratory of Breast Cancer

the Training Plan of Excellent Talents in Shanghai Municipality Health System

the Training Plan of Excellent Talents of Fudan University Shanghai Cancer Center

the “Chen Guang” project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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