Dynamic detection and reversal of myocardial ischemia using an artificially intelligent bioelectronic medicine

Author:

Ganzer Patrick D.123ORCID,Loeian Masoud S.1ORCID,Roof Steve R.4ORCID,Teng Bunyen4ORCID,Lin Luan5,Friedenberg David A.5ORCID,Baumgart Ian W.1ORCID,Meyers Eric C.1,Chun Keum S.1ORCID,Rich Adam5,Tsao Allison L.67ORCID,Muir William W.48ORCID,Weber Doug J.9ORCID,Hamlin Robert L.410ORCID

Affiliation:

1. Medical Devices and Neuromodulation, Battelle Memorial Institute, 505 King Ave., Columbus, OH 43201, USA.

2. Department of Biomedical Engineering, University of Miami, 1320 S Dixie Hwy., Coral Gables, FL 33146, USA.

3. The Miami Project to Cure Paralysis, University of Miami, 1095 NW 14th Terrace #48, Miami, FL 33136, USA.

4. QTest Labs, 6456 Fiesta Dr., Columbus, OH 43235, USA.

5. Health Analytics, Battelle Memorial Institute, 505 King Ave., Columbus, OH 43201, USA.

6. Cardiovascular Section, Department of Medicine, VA Boston Healthcare System, Boston, MA 02130, USA.

7. Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.

8. College of Veterinary Medicine, Lincoln Memorial University, 6965 Cumberland Gap Parkway, Harrogate, TN 37752, USA.

9. Department of Mechanical Engineering and Neuroscience, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213, USA.

10. Department of Veterinary Biosciences, The Ohio State University, 1900 Coffey Road, Columbus, OH 43201, USA.

Abstract

Potentially damaging “heart stress” is reversed using reactive nerve stimulation controlled by artificial intelligence.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference93 articles.

1. World Health Organization Global Health Estimates 2016: Deaths by cause age sex by country and by region 2000-2016 (World Health Organization 2018).

2. Myocardial Oxygen Supply and Demand* *Cardiovascular Research Institute, and Division of Cardiology, Department of Medicine, University of California, San Francisco.

3. Role of myocardial oxygen demand in the pathogenesis of silent ischemia during daily life

4. Myocardial ischemia during daily activities: The importance of increased myocardial oxygen demand

5. Stable coronary artery disease: Treatment;Braun M. M.;Am. Fam. Physician,2018

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