Anti-α 4 β 7 monoclonal antibody–conjugated nanoparticles block integrin α 4 β 7 on intravaginal T cells in rhesus macaques-Reference-Cited by-同舟云学术

Anti-α 4 β 7 monoclonal antibody–conjugated nanoparticles block integrin α 4 β 7 on intravaginal T cells in rhesus macaques

Published:2020-08-21 Issue:34 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Yang Sidi¹^ORCID,Arrode-Bruses Geraldine²^ORCID,Frank Ines²^ORCID,Grasperge Brooke³^ORCID,Blanchard James³^ORCID,Gettie Agegnehu⁴,Martinelli Elena²^ORCID,Ho Emmanuel A.¹^ORCID

Affiliation:

1. School of Pharmacy, University of Waterloo, 10 Victoria St. S A, Kitchener, Ontario N2G 1C5, Canada.

2. Center for Biomedical Research, Population Council, One Dag Hammarskjold Plaza, New York, NY 10017, USA.

3. Tulane National Primate Research Center, Tulane University, 6823 St. Charles Ave., New Orleans, LA 70118, USA.

4. Aaron Diamond AIDS Research Center, Rockefeller University, 455 1st Avenue #7, New York, NY 10016, USA.

Abstract

Anti-α 4 β 7 monoclonal antibody–conjugated nanoparticles block integrin α 4 β 7 on intravaginal T cells in rhesus macaques.

Funder

Canadian Institutes of Health Research

National Institutes of Health Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference53 articles.

1. Integrins

2. LPAM (α4β7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease

3. α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

4. Lymphocyte Homing and Homeostasis

5. HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

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