ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Author:

Even Aviel1ORCID,Morelli Giovanni23ORCID,Broix Loïc2ORCID,Scaramuzzino Chiara45ORCID,Turchetto Silvia2,Gladwyn-Ng Ivan2,Le Bail Romain2ORCID,Shilian Michal1ORCID,Freeman Stephen2,Magiera Maria M.67ORCID,Jijumon A. S.67ORCID,Krusy Nathalie2,Malgrange Brigitte2ORCID,Brone Bert3ORCID,Dietrich Paula8,Dragatsis Ioannis8,Janke Carsten67ORCID,Saudou Frédéric459ORCID,Weil Miguel1ORCID,Nguyen Laurent2ORCID

Affiliation:

1. Laboratory for Neurodegenerative Diseases and Personalized Medicine, Department of Cell Research and Immunology, The George S. Wise Faculty for Life Sciences, Sagol School of Neurosciences, Tel Aviv University, Ramat Aviv 69978, Israel.

2. GIGA-Stem Cells and GIGA-Neurosciences, Interdisciplinary Cluster for Applied Genoproteomics (GIGA-R), University of Liège, CHU Sart Tilman, Liège 4000, Belgium.

3. BIOMED Research Institute, University of Hasselt, Hasselt 3500, Belgium.

4. Grenoble Institut des Neurosciences, GIN, Univ. Grenoble Alpes, F-38000 Grenoble, France.

5. Inserm, U1216, F-38000 Grenoble, France.

6. Institut Curie, PSL Research University, CNRS UMR 3348, F-91405 Orsay, France.

7. Université Paris-Sud, Université Paris-Saclay, CNRS UMR3348, F-91405 Orsay, France.

8. Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

9. CHU Grenoble Alpes, F-38000 Grenoble, France.

Abstract

The axonal transport of vesicles promotes microtubule acetylation across species.

Funder

Israel Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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