ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization-Reference-Cited by-同舟云学术

ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization

Published:2020-07-31 Issue:31 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Lam Hiu Yan¹²^ORCID,Arumugam Surendar¹,Bae Han Gyu³^ORCID,Wang Cheng Chun⁴,Jung Sangyong³^ORCID,St. John Ashley Lauren⁵⁶⁷^ORCID,Hong Wanjin⁴^ORCID,Han Weiping³^ORCID,Tergaonkar Vinay¹⁸^ORCID

Affiliation:

1. Laboratory of NF-κB Signaling, Institute of Molecular and Cell Biology (IMCB), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.

2. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 117596, Singapore.

3. Singapore Bioimaging Consortium, Agency for Science, Technology and Research, #02-02 Helios, 11 Biopolis Way, Singapore 138667, Singapore.

4. Institute of Molecular and Cell Biology (IMCB), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.

5. Program in Emerging Infectious Diseases, Duke-NUS, Singapore 169857, Singapore.

6. Department of Microbiology and Immunology, NUS, Singapore 119077, Singapore.

7. Department of Pathology, Duke University Medical Center, Durham, NC, USA.

8. Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119074, Singapore.

Abstract

ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization.

Funder

National Research Foundation

Agency for Science, Technology and Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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