N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance

Author:

Liberman Noa12ORCID,O’Brown Zach K.12ORCID,Earl Andrew Scott12ORCID,Boulias Konstantinos12,Gerashchenko Maxim V.3ORCID,Wang Simon Yuan12ORCID,Fritsche Colette1ORCID,Fady Paul-Enguerrand1ORCID,Dong Anna1,Gladyshev Vadim N.3ORCID,Greer Eric Lieberman12ORCID

Affiliation:

1. Division of Newborn Medicine, Boston Children’s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.

2. Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

3. Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

Abstract

18 S ribosomal RNA methylation by METL-5 regulates lipid oxidation and stress resistance in C. elegans .

Funder

National Institutes of Health

American Federation for Aging Research

Croucher Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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