Engineered algae: A novel oxygen-generating system for effective treatment of hypoxic cancer-Reference-Cited by-同舟云学术

Engineered algae: A novel oxygen-generating system for effective treatment of hypoxic cancer

Published:2020-05-22 Issue:21 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Qiao Yue¹²^ORCID,Yang Fei¹^ORCID,Xie Tingting²^ORCID,Du Zhen²,Zhong Danni²,Qi Yuchen²,Li Yangyang²,Li Wanlin²³,Lu Zhimin²,Rao Jianghong³^ORCID,Sun Yi²⁴^ORCID,Zhou Min¹²⁴⁵^ORCID

Affiliation:

1. Eye Center & Key Laboratory of Cancer Prevention and Intervention, MOE, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310029, China.

2. Institute of Translational Medicine and The Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310029, China.

3. Department of Radiology and Bio-X, Stanford University, Stanford, CA 94305, USA.

4. Division of Radiation and Cancer Biology, Department of Radiation Oncology 94305, University of Michigan, Ann Arbor, MI 48109, USA.

5. State Key Laboratory of Modern Optical Instrumentations, Zhejiang University, Hangzhou 310058, China.

Abstract

Engineered living microalgae can relieve tumor hypoxia in situ and sensitize tumor cells to radiation and photodynamic therapies.

Funder

National Key Research and Development Program of China Stem Cell and Translational Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference47 articles.

1. The impact of O2 availability on human cancer

2. Physiological Effects of Chronic Hypoxia

3. The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence

4. Opportunities and challenges of radiotherapy for treating cancer

5. Mechanisms of Resistance to Photodynamic Therapy

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