PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly-Reference-Cited by-同舟云学术

PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly

Published:2020-01-10 Issue:2 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Mzoughi Slim¹²^ORCID,Di Tullio Federico¹^ORCID,Low Diana H. P.¹^ORCID,Motofeanu Corina-Mihaela¹,Ong Sheena L. M.³^ORCID,Wollmann Heike¹,Wun Cheng Mun¹,Kruszka Paul⁴,Muenke Maximilian⁴^ORCID,Hildebrandt Friedhelm⁵,Dunn N. Ray³^ORCID,Messerschmidt Daniel M.¹,Guccione Ernesto¹²⁶⁷^ORCID

Affiliation:

1. Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.

2. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

3. Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore.

4. Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

5. Department of Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

6. Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

7. Department of Pharmacological Sciences and Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Abstract

The transcriptional regulator PRDM15 orchestrates NOTCH and WNT/PCP signaling to ensure normal mammalian development.

Funder

NMRC

NRF Singapore

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Describing the Prevalence of Neural Tube Defects Worldwide: A Systematic Literature Review

2. Global burden of neural tube defects, risk factors, and prevention;Flores A. L.;Indian J Community Health,2014

3. Estimates of global and regional prevalence of neural tube defects for 2015: a systematic analysis

4. B. D. Solomon A. Gropman M. Muenke Holoprosencephaly overview in GeneReviews(R) M. P. Adam R. A. Pagon H. H. Ardinger T. D. Bird C. R. Dolan C. T. Fong Eds. (University of Washington 1993).

5. The molecular genetics of holoprosencephaly

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis;Frontiers in Cell and Developmental Biology;2024-02-20

2. Multi-omics analysis reveals signatures of selection and loci associated with complex traits in pigs;2023-09-21

3. Transcription factor PRDM15 binds to the promoter mutation locus of PPP2R5C promoted proliferation of goat granulosa cells;2023-01-25

4. Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15;International Journal of Molecular Sciences;2023-01-10

5. PRDM15 interacts with DNA-PK-Ku complex to promote radioresistance in rectal cancer by facilitating DNA damage repair;Cell Death & Disease;2022-11-19