Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease-Reference-Cited by-同舟云学术

Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease

Published:2019-08-02 Issue:8 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Goel Gautam¹^ORCID,Tye-Din Jason A.²³⁴⁵^ORCID,Qiao Shuo-Wang⁶,Russell Amy K.²,Mayassi Toufic⁷^ORCID,Ciszewski Cezary⁷,Sarna Vikas K.⁶^ORCID,Wang Suyue⁸^ORCID,Goldstein Kaela E.⁸^ORCID,Dzuris John L.⁸^ORCID,Williams Leslie J.⁸^ORCID,Xavier Ramnik J.¹^ORCID,Lundin Knut E. A.⁹^ORCID,Jabri Bana⁷^ORCID,Sollid Ludvig M.⁶^ORCID,Anderson Robert P.⁸^ORCID

Affiliation:

1. Division of Gastroenterology and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.

2. Immunology Division, The Walter and Eliza Hall Institute, Parkville, VIC, Australia.

3. Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.

4. Department of Gastroenterology, The Royal Melbourne Hospital, Parkville, VIC, Australia.

5. Centre for Food and Allergy Research, Murdoch Children’s Research Institute, Parkville, VIC, Australia.

6. Department of Immunology and KG Jebsen Coeliac Disease Research Centre, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway.

7. Department of Pediatrics, Department of Medicine, University of Chicago, Chicago, IL, USA.

8. ImmusanT Inc., Cambridge, MA, USA.

9. Department of Gastroenterology and KG Jebsen Coeliac Disease Research Centre, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, Norway.

Abstract

Acute gastrointestinal symptoms induced by gluten, within 4 hours, are mediated by reactivation of antigen-specific memory T cells.

Funder

National Institutes of Health

Digestive Diseases Research Core Center, University of Chicago

The Research Council

Research Council of Norway

Stiftelsen KG Jebsen

The South-Eastern Norway Regional Health Authority

The Paul and Kathy Severino Research Fund at Massachusetts General Hospital

The Mathison Centenary Fellowship, University of Melbourne

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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