Efficient aortic lymphatic drainage is necessary for atherosclerosis regression induced by ezetimibe-Reference-Cited by-同舟云学术

Efficient aortic lymphatic drainage is necessary for atherosclerosis regression induced by ezetimibe

Published:2020-12-11 Issue:50 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Yeo Kim Pin¹²^ORCID,Lim Hwee Ying¹²^ORCID,Thiam Chung Hwee¹²,Azhar Syaza Hazwany¹²,Tan Caris³,Tang Ya¹²,See Wei Qiang¹²,Koh Xuan Han¹²,Zhao Ming Hao¹²,Phua Meow Ling⁴,Balachander Akhila⁴^ORCID,Tan Yingrou⁴^ORCID,Lim Sheau Yng¹²^ORCID,Chew Hui Shang¹²,Ng Lai Guan¹²^ORCID,Angeli Veronique¹²^ORCID

Affiliation:

1. Immunology Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

2. Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

3. Histology Core Facility, Life Sciences Institute, National University of Singapore, Singapore, Singapore.

4. Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.

Abstract

The results show that a functional lymphatic drainage of the aorta is critical to inhibit atherosclerosis progression and mediate its regression.

Funder

National Medical Research Council

Ministry of Education Singapore

National research association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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