Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction

Author:

Botting K. J.123ORCID,Skeffington K. L.13ORCID,Niu Y.123,Allison B. J.13ORCID,Brain K. L.13ORCID,Itani N.13ORCID,Beck C.13,Logan A.4ORCID,Murray A. J.1ORCID,Murphy M. P.4ORCID,Giussani D. A.1235ORCID

Affiliation:

1. Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.

2. Cambridge Cardiovascular Strategic Research Initiative, Cambridge, UK.

3. Barcroft Centre, University of Cambridge, Cambridge, UK.

4. MRC-Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.

5. Cambridge Strategic Research Initiative in Reproduction, Cambridge, UK.

Abstract

Mitochondrial therapy may cure hypertension in adult offspring of complicated pregnancies.

Funder

Medical Research Council

The Wellcome Trust

The British Heart Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Conference Board of Canada “The Canadian heart health strategy: Risk factors and future cost implications” (Report 2010 Conference Board of Canada 2010).

2. European Heart Network and European Society of Cardiology European Cardiovascular Disease Statistics (European Heart Network and European Society of Cardiology 2012).

3. D. J. Barker Mothers Babies and Disease in Later Life (Churchill Livingstone 1998).

4. Effect of In Utero and Early-Life Conditions on Adult Health and Disease

5. Developmental programming of cardiovascular disease by prenatal hypoxia

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