Trisulfide bond–mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity-Reference-Cited by-同舟云学术

Trisulfide bond–mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity

Published:2020-11-06 Issue:45 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Yang Yinxian¹^ORCID,Sun Bingjun²^ORCID,Zuo Shiyi²,Li Ximu²,Zhou Shuang²,Li Lingxiao²,Luo Cong²,Liu Hongzhuo²,Cheng Maosheng³,Wang Yongjun²^ORCID,Wang Shujun¹,He Zhonggui²,Sun Jin²^ORCID

Affiliation:

1. Department of Pharmaceutics, College of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.

2. Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.

3. Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.

Abstract

Trisulfide bond enhances the stability and GSH sensitivity of doxorubicin dimeric prodrug nanoassemblies.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

LiaoNing Revitalization Talents Program

China Postdoctoral Innovative Talents Support Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Smart cancer nanomedicine

2. Clinical Translation of Nanomedicine

3. Evolution and clinical translation of drug delivery nanomaterials

4. Cancer nanomedicine: progress, challenges and opportunities

5. Challenges in design of translational nanocarriers

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