OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification-Reference-Cited by-同舟云学术

OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification

Published:2021-11-05 Issue:45 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Farrar Emily J.¹^ORCID,Hiriart Emilye²^ORCID,Mahmut Ablajan¹^ORCID,Jagla Bernd³^ORCID,Peal David S.⁴,Milan David J.⁴,Butcher Jonathan T.¹^ORCID,Puceat Michel²^ORCID

Affiliation:

1. Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA.

2. INSERM U1251, Aix-Marseille University, MMG, Marseille, France.

3. Pasteur Institute, Cytometry and Biomarkers Unit of Technology and Service, C2RT, & Hub de Bioinformatique et Biostatistique–Département Biologie Computationnelle, Paris, France.

4. Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.

Abstract

Cell reprogramming is at the origin of valve calcification.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference57 articles.

1. Single-Cell (Multi)omics Technologies

2. Heart Valve Development

3. Heart Valve Structure and Function in Development and Disease

4. Transcriptional Regulation of Heart Valve Progenitor Cells

5. Congenital Heart Disease: Incidence and Inheritance

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