Recruitment of CD103 + dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy-Reference-Cited by-同舟云学术

Recruitment of CD103 + dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

Published:2019-12-06 Issue:12 Volume:5 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Williford John-Michael¹^ORCID,Ishihara Jun¹^ORCID,Ishihara Ako¹^ORCID,Mansurov Aslan¹^ORCID,Hosseinchi Peyman¹^ORCID,Marchell Tiffany M.¹²^ORCID,Potin Lambert¹³^ORCID,Swartz Melody A.¹²⁴^ORCID,Hubbell Jeffrey A.¹²^ORCID

Affiliation:

1. Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637, USA.

2. Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.

3. Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

4. Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.

Abstract

Targeted delivery of CCL4 to the tumor stroma recruits CD103 + dendritic cells and enhances the efficacy of CPI immunotherapy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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