Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective-Reference-Cited by-同舟云学术

Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective

Published:2020-07-17 Issue:29 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Verry Camille¹^ORCID,Dufort Sandrine²,Lemasson Benjamin³^ORCID,Grand Sylvie¹,Pietras Johan⁴^ORCID,Troprès Irène⁴^ORCID,Crémillieux Yannick⁵^ORCID,Lux François⁶,Mériaux Sébastien⁷^ORCID,Larrat Benoit⁷,Balosso Jacques¹^ORCID,Le Duc Géraldine²^ORCID,Barbier Emmanuel L.³^ORCID,Tillement Olivier⁶

Affiliation:

1. CHU Grenoble Alpes, Grenoble, France.

2. NH TherAguix, Meylan, France.

3. Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, Grenoble, France.

4. IRMaGe, CNRS, INSERM, Université Grenoble Alpes, CHU Grenoble Alpes, Grenoble, France.

5. Institut des Sciences Moléculaires, CNRS, Université de Bordeaux, Bordeaux, France.

6. Institut Lumière Matière, CNRS, Université de Lyon, Villeurbanne, France.

7. NeuroSpin, CEA, Université Paris-Saclay, Gif-sur-Yvette, France.

Abstract

Intravenously injected theranostic Gd-based nanoparticles enable targeting and MRI detection of brain metastases in patients.

Funder

NH Theraguix

Centre Hospitalier Universitaire de Grenoble

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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