In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer-Reference-Cited by-同舟云学术

In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer

Published:2021-07-02 Issue:27 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Bock Nathalie¹²³⁴⁵^ORCID,Kryza Thomas¹²³^ORCID,Shokoohmand Ali¹²³⁴,Röhl Joan¹²³^ORCID,Ravichandran Akhilandeshwari²³⁴^ORCID,Wille Marie-Luise²⁵⁶^ORCID,Nelson Colleen C.¹²³^ORCID,Hutmacher Dietmar W.¹³⁴⁵⁶^ORCID,Clements Judith A.¹²³^ORCID

Affiliation:

1. School of Biomedical Sciences, Faculty of Health and Australian Prostate Cancer Research Centre (APCRC-Q), Brisbane 4000, QLD, Australia.

2. Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology (QUT), Brisbane 4000, QLD, Australia.

3. Translational Research Institute (TRI), QUT, Woolloongabba, 4102 QLD, Australia.

4. Centre in Regenerative Medicine, IHBI, QUT, Kelvin Grove, 4059 QLD, Australia.

5. Australian Research Council (ARC) Training Centre for Multiscale 3D Imaging, Modelling and Manufacturing (M3D Innovation), QUT, Kelvin Grove, 4059 QLD, Australia.

6. Bone and Joint Disorders Program, School of Mechanical Medical, and Process Engineering, Science and Engineering Faculty (SEF), QUT, Brisbane, 4000 QLD, Australia.

Abstract

In vitro engineering of a bone metastases model allows us to study the effects of antiandrogens in advanced prostate cancer.

Funder

Lush

Australian Research Council

National Health and Medical Research Council

Prostate Cancer Foundation of Australia

Australian Research Council Industrial Transformation Training Center in Additive Biomanufacturing

Movember Revolutionary Team Award

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference54 articles.

1. Managing bone metastases and reducing skeletal related events in prostate cancer

2. Targeting bone metastases in prostate cancer: improving clinical outcome

3. Androgen Receptor in Prostate Cancer

4. Prostate‐specific antigen modulates the osteogenic differentiation of MSCs via the cadherin 11‐Akt axis

5. Enzalutamide and blocking androgen receptor in advanced prostate cancer: Lessons learnt from the history of drug development of antiandrogens;Ito Y.;Res. Rep. Urol.,2018

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