Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

Author:

Song You-Hyang1ORCID,Hwang Yang-Sun1ORCID,Kim Kwansoo1ORCID,Lee Hyoung-Ro2ORCID,Kim Jae-Hyun1ORCID,Maclachlan Catherine3,Dubois Anaelle3,Jung Min Whan4ORCID,Petersen Carl C. H.5ORCID,Knott Graham3ORCID,Lee Suk-Ho2ORCID,Lee Seung-Hee1ORCID

Affiliation:

1. Department of Biological Sciences, KAIST, Daejeon 34141, Republic of Korea.

2. Department of Physiology, Seoul National University College of Medicine, Seoul, Republic of Korea.

3. Biological Electron Microscopy Facility, Centre of Electron Microscopy, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

4. Center for Synaptic Brain Dysfunctions, Institute for Basic Science and Department of Biological Sciences, KAIST, Daejeon 34141, Republic of Korea.

5. Brain Mind Institute, Faculty of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Abstract

Somatostatin improves visual perception by reducing excitatory inputs to the parvalbumin-positive interneurons in the cortex.

Funder

National Research Foundation of Korea

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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