In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation-Reference-Cited by-同舟云学术

In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

Published:2020-03-13 Issue:11 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Fisher James D.¹²^ORCID,Zhang Wensheng³^ORCID,Balmert Stephen C.¹⁴^ORCID,Aral Ali M.¹⁵^ORCID,Acharya Abhinav P.⁶,Kulahci Yalcin⁶^ORCID,Li Jingjing³,Turnquist Heth R.⁵⁷⁸⁹^ORCID,Thomson Angus W.⁵⁷⁸,Solari Mario G.³⁹^ORCID,Gorantla Vijay S.¹⁰^ORCID,Little Steven R.¹⁶⁸⁹¹¹^ORCID

Affiliation:

1. Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.

2. Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, PA, USA.

3. Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

4. Department of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA.

5. Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

6. Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA, USA.

7. Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA.

8. Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.

9. McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

10. Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA.

11. Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.

Abstract

CCL22-releasing microparticles recruit suppressive immune cells to transplanted rat limbs to promote long-term graft survival.

Funder

U.S. Department of Defense

National Cancer Institute

National Institute of Allergy and Infectious Diseases

National Institute of Dental and Craniofacial Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

1. Bilateral Trans-humeral Arm Transplantation: Result at 2 Years

2. The International Registry on Hand and Composite Tissue Transplantation

3. Immunological Issues in Clinical Composite Tissue Allotransplantation

4. Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

5. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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