Switchable immune modulator for tumor-specific activation of anticancer immunity-Reference-Cited by-同舟云学术

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Switchable immune modulator for tumor-specific activation of anticancer immunity

Published:2021-09-10 Issue:37 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zhao Yu¹²^ORCID,Xie Yu-Qing¹^ORCID,Van Herck Simon¹³,Nassiri Sina⁴,Gao Min¹^ORCID,Guo Yugang¹²^ORCID,Tang Li¹²^ORCID

Affiliation:

1. Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

2. Institute of Materials Science & Engineering, EPFL, 1015 Lausanne, Switzerland.

3. Department of Pharmaceutics, Ghent University, 9000 Ghent, Belgium.

4. Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.

Abstract

Chemically masked cytokines and antibodies turn active selectively in tumor as safer cancer immunotherapies.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference56 articles.

1. Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody

2. Side Effects of Cytokines Approved for Therapy

3. IL-15 Superagonist–Mediated Immunotoxicity: Role of NK Cells and IFN-γ

4. Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies

5. IL-15 enhances thein vivoantitumor activity of tumor-reactive CD8+T Cells

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