A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation-Reference-Cited by-同舟云学术

A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation

Published:2020-05-22 Issue:21 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Niu Liman¹^ORCID,Lou Fangzhou¹^ORCID,Sun Yang¹^ORCID,Sun Libo¹^ORCID,Cai Xiaojie¹,Liu Zhaoyuan¹^ORCID,Zhou Hong¹,Wang Hong¹,Wang Zhikai¹,Bai Jing¹,Yin Qianqian¹,Zhang Junxun¹,Chen Linjiao²,Peng Danhong²^ORCID,Xu Zhenyao¹,Gao Yuanyuan¹,Tang Sibei¹,Fan Li¹,Wang Honglin¹^ORCID

Affiliation:

1. Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China.

2. Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.

Abstract

A micropeptide encoded by MIR155HG modulates antigen presentation and suppresses autoinflammation through binding to HSC70.

Funder

National Natural Science Foundation of China

Shanghai Collaborative Innovation Center for Translational Medicine

Innovative research team of high-level local universities in Shanghai

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference32 articles.

1. MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity

2. How B cells capture, process and present antigens: a crucial role for cell polarity

3. The ins and outs of MHC class II-mediated antigen processing and presentation

4. Polarized Secretion of Lysosomes at the B Cell Synapse Couples Antigen Extraction to Processing and Presentation

5. Nuclear Hormone Receptors Enable Macrophages and Dendritic Cells to Sense Their Lipid Environment and Shape Their Immune Response

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