The energy landscape of −1 ribosomal frameshifting-Reference-Cited by-同舟云学术

The energy landscape of −1 ribosomal frameshifting

Published:2020-01-03 Issue:1 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Choi Junhong¹²^ORCID,O’Loughlin Sinéad³^ORCID,Atkins John F.³⁴^ORCID,Puglisi Joseph D.¹^ORCID

Affiliation:

1. Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305-5126, USA.

2. Department of Applied Physics, Stanford University, Stanford, CA 94305-4090, USA.

3. Schools of Biochemistry and Microbiology, University College Cork, Western Gateway Building, Western Road, Cork, Ireland.

4. Department of Human Genetics, University of Utah, Salt Lake City, UT 84112-5330, USA.

Abstract

During translation, the presence of an mRNA structure prolongs a ribosomal state favorable to spontaneous frameshifting.

Funder

National Institute of General Medical Sciences

Stanford Bio-X

Science Foundation Ireland

Irish Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference47 articles.

1. Low Activity of -Galactosidase in Frameshift Mutants of Escherichia coli

2. Processivity errors of gene expression in Escherichia coli

3. Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use;Atkins J. F.;Nucleic Acids Res.,2016

4. J. F. Atkins R. F. Gesteland Recoding: Expansion of Decoding Rules Enriches Gene Expression (Springer Verlag New 2010).

5. Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

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