FDISCO: Advanced solvent-based clearing method for imaging whole organs

Author:

Qi Yisong12ORCID,Yu Tingting12ORCID,Xu Jianyi12,Wan Peng12,Ma Yilin12,Zhu Jingtan12ORCID,Li Yusha12,Gong Hui12,Luo Qingming12,Zhu Dan12ORCID

Affiliation:

1. Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, Hubei, China.

2. MoE Key Laboratory for Biomedical Photonics, Collaborative Innovation Center for Biomedical Engineering, School of Engineering Sciences, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Abstract

We developed an advanced clearing method with superior fluorescence-preserving capability for 3D imaging of whole organs.

Funder

National Key Research and Development Program of China

National Nature Science Foundation of China

Project funded by China Postdoctoral Science Foundation

Director Fund of WNLO

Fundamental Research Funds for the Central Universities, HUST

Science Fund for Creative Research Group of China

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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