Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5-Reference-Cited by-同舟云学术

Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5

Author:

Terzi Erdem M.¹²^ORCID,Sviderskiy Vladislav O.¹²^ORCID,Alvarez Samantha W.¹²,Whiten Gabrielle C.¹²^ORCID,Possemato Richard¹²^ORCID

Affiliation:

1. Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.

2. Laura and Isaac Perlmutter Cancer Center, New York, NY 10016, USA.

Abstract

Iron-sulfur clusters enable cells to sense that they have the right amount of iron, and protect them from self-destruction.

Funder

National Institutes of Health

Alexander and Margaret Stewart Trust

Friedreich’s Ataxia Research Alliance

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference33 articles.

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