Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

Author:

Ben-Akiva Elana12ORCID,Meyer Randall A.1,Yu Hongzhe1,Smith Jonathan T.1,Pardoll Drew M.23ORCID,Green Jordan J.12ORCID

Affiliation:

1. Departments of Biomedical Engineering, Materials Science and Engineering, Chemical and Biomolecular Engineering, and Oncology, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins School of Medicine, 400 N Broadway, Smith Building 5017, Baltimore, MD 21231, USA.

2. Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

3. Departments of Oncology, Medicine, Pathology and Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

Abstract

Red blood cell–mimicking nanoparticles with different shapes effectively soak up toxins from the blood to prevent sepsis.

Funder

National Science Foundation

National Institutes of Health

Achievement Rewards for College Scientists Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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