Gastrointestinal-resident, shape-changing microdevices extend drug release in vivo-Reference-Cited by-同舟云学术

Gastrointestinal-resident, shape-changing microdevices extend drug release in vivo

Published:2020-10-30 Issue:44 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Ghosh Arijit¹^ORCID,Li Ling²^ORCID,Xu Liyi¹^ORCID,Dash Ranjeet P.³⁴,Gupta Neha¹^ORCID,Lam Jenny³⁴^ORCID,Jin Qianru¹^ORCID,Akshintala Venkata²^ORCID,Pahapale Gayatri¹^ORCID,Liu Wangqu¹^ORCID,Sarkar Anjishnu¹^ORCID,Rais Rana³⁴^ORCID,Gracias David H.¹⁵⁶^ORCID,Selaru Florin M.²^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

2. Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

3. Johns Hopkins Drug Discovery, Baltimore, MD 21205, USA.

4. Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

5. Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

6. Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA.

Abstract

Hookworm inspired, autonomous latching on the gastrointestinal mucosa extends the in vivo retention of a drug delivery device.

Funder

National Science Foundation

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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