The IgM pentamer is an asymmetric pentagon with an open groove that binds the AIM protein-Reference-Cited by-同舟云学术

The IgM pentamer is an asymmetric pentagon with an open groove that binds the AIM protein

Published:2018-10-05 Issue:10 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Hiramoto Emiri¹^ORCID,Tsutsumi Akihisa²^ORCID,Suzuki Risa¹^ORCID,Matsuoka Shigeru¹,Arai Satoko¹^ORCID,Kikkawa Masahide²^ORCID,Miyazaki Toru¹³⁴^ORCID

Affiliation:

1. Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

2. Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

3. AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan.

4. Max Planck–The University of Tokyo Center for Integrative Inflammology, Tokyo, Japan.

Abstract

We demonstrate the bona fide 2D structure of the IgM pentamer and its association with AIM protein.

Funder

Japan Agency for Medical Research and Development

MEXT Grant-in-Aid for Scientific Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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