New power of self-assembling carbonic anhydrase inhibitor: Short peptide–constructed nanofibers inspire hypoxic cancer therapy

Author:

Li Jiayang1ORCID,Shi Kejian1ORCID,Sabet Zeinab Farhadi12,Fu Wenjiao1ORCID,Zhou Huige1,Xu Shaoxin1ORCID,Liu Tao1,You Min1ORCID,Cao Mingjing1ORCID,Xu Mengzhen1,Cui Xuejing1,Hu Bin1,Liu Ying1ORCID,Chen Chunying12ORCID

Affiliation:

1. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, People’s Republic of China.

2. University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China.

Abstract

Self-assembly of CA inhibitor offers strategic therapy for hypoxic tumors, with marked selectivity and interesting mode of action.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

The National Science Fund for Excellent Young Scholars

The National Science Fund for Distinguished Young Scholars

Science Fund for Creative Research Groups of the National Natural Science Foundation of China

CAS Key Research Program for Frontier Sciences

Key Program for International S&T Cooperation Projects of China

Bureau of International Co-operation Chinese Academy of Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference43 articles.

1. The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy;Brown J. M.;Cancer Res.,1998

2. The hypoxic tumour microenvironment and metastatic progression;Subarsky P.;Clin. Exp. Metastasis,2003

3. Mechanical approaches to oncological drug delivery;Carlisle R.;Ther. Deliv.,2013

4. Targeting hypoxia in cancer therapy

5. Carbonic anhydrase IX inhibitors in cancer therapy: An update;Supuran C. T.;Future Med. Chem.,2015

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3