A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting-Reference-Cited by-同舟云学术

A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting

Published:2021-02-05 Issue:6 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

He Yanmei¹^ORCID,Lei Lei¹²^ORCID,Cao Jun¹³^ORCID,Yang Xiaotong²^ORCID,Cai Shengsheng¹^ORCID,Tong Fan²^ORCID,Huang Dennis³^ORCID,Mei Heng¹^ORCID,Luo Kui⁴^ORCID,Gao Huile²^ORCID,He Bin¹^ORCID,Peppas Nicholas A.³⁵^ORCID

Affiliation:

1. National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, P. R. China.

2. West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China.

3. Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78731, USA.

4. Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China.

5. Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, TX 78731, USA.

Abstract

Nanoparticulate-based combinatorial therapy induced robust antitumor immunity against tumor metastasis.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China Stem Cell and Translational Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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