Protein lysine de-2-hydroxyisobutyrylation by CobB in prokaryotes

Author:

Dong Hanyang1ORCID,Zhai Guijin1,Chen Cong1,Bai Xue1,Tian Shanshan1,Hu Deqing12ORCID,Fan Enguo3,Zhang Kai1ORCID

Affiliation:

1. 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, Key Laboratory of Breast Cancer Prevention and Treatment (Ministry of Education), Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China

2. Tianjin Key Laboratory of Medical Epigenetics, Department of Cell Biology, Tianjin Medical University, Tianjin, China

3. Institut für Biochemie und Molekularbiologie, Universität Freiburg, Freiburg, Germany

Abstract

CobB serves as a lysine de-2-hydroxyisobutyrylation enzyme to regulate metabolism and cell growth in prokaryotes.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin Municipal Science and Technology Commission

National Basic Research Program of China

Talent Excellence Program from Tianjin Medical University

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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