Damaged lung gas exchange function of discharged COVID-19 patients detected by hyperpolarized 129 Xe MRI

Author:

Li Haidong1ORCID,Zhao Xiuchao1,Wang Yujin2ORCID,Lou Xin3ORCID,Chen Shizhen1,Deng He1ORCID,Shi Lei1ORCID,Xie Junshuai1,Tang Dazhong2ORCID,Zhao Jianping2,Bouchard Louis-S.4,Xia Liming2ORCID,Zhou Xin1ORCID

Affiliation:

1. Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan National Laboratory for Optoelectronics, Wuhan 430071, P. R. China.

2. Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P. R. China.

3. Department of Radiology, Chinese PLA General Hospital, Beijing 100853, P. R. China.

4. Jonsson Comprehensive Cancer Center, The Molecular Biology Institute, California NanoSystems Institute, Departments of Chemistry and Biochemistry and of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Abstract

Functional imaging of the lungs in COVID-19 patients shows altered gas exchange function.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China Stem Cell and Translational Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference37 articles.

1. Chinese Center for Disease Control and Prevention Distribution of coronavirus disease 2019 (2020); http://2019ncov.chinacdc.cn/2019-nCoV/.

2. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

3. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

4. Scientists are racing to model the next moves of a coronavirus that’s still hard to predict;Cohen J.;Science,2020

5. World Health Organization Coronavirus disease 2019 (COVID-19) situation report–147 (2020); www.who.int/docs/default-source/coronaviruse/situation-reports/20200615-covid-19-sitrep-147.pdf?sfvrsn=2497a605_4.

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