SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity

Author:

Wang Ning1ORCID,Tan Hor-Yue1,Li Sha1,Wang Di2ORCID,Xu Yu1,Zhang Cheng1,Xia Wen3,Che Chi-Ming4,Feng Yibin1ORCID

Affiliation:

1. School of Chinese Medicine, The University of Hong Kong, 1/F, 10 Sassoon Road, Pokfulam, Hong Kong S.A.R. 00000, P.R. China.

2. School of Life Science and State Engineering Laboratory of AIDS Vaccine, Jilin University, Changchun, Jilin Province 130012, P.R. China.

3. Joint Research Center for National and Local Miao Drug, Anshun, Guizhou Province 561000, P.R. China.

4. Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China.

Abstract

SBP2 loss in macrophages drives adipose tissue inflammation and insulin resistance during obesity.

Funder

Health and Medical Research Fund

Research Council of the University of Hong Kong

Wong’s donation

Gaia Family Trust of New Zealand

Bailing Pharmaceutical Group & Co.

Research Grants Committee of Hong Kong

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

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