In vivo priming of human mesenchymal stem cells with hepatocyte growth factor–engineered mesenchymal stem cells promotes therapeutic potential for cardiac repair-Reference-Cited by-同舟云学术

In vivo priming of human mesenchymal stem cells with hepatocyte growth factor–engineered mesenchymal stem cells promotes therapeutic potential for cardiac repair

Published:2020-03-27 Issue:13 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Park Bong-Woo¹²^ORCID,Jung Soo-Hyun¹²,Das Sanskrita³^ORCID,Lee Soon Min⁴^ORCID,Park Jae-Hyun¹²,Kim Hyeok¹²^ORCID,Hwang Ji-Won¹²^ORCID,Lee Sunghun⁵^ORCID,Kim Hyo-Jin⁴^ORCID,Kim Hey-Yon⁴^ORCID,Jung Seungman³⁶,Cho Dong-Woo⁷,Jang Jinah³⁶⁷^ORCID,Ban Kiwon⁵^ORCID,Park Hun-Jun¹²⁸^ORCID

Affiliation:

1. Department of Medical Life Science, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137701, Republic of Korea.

2. Division of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137701, Republic of Korea.

3. Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Namgu, Pohang, Kyungbuk 37673, Republic of Korea.

4. SL BIGEN Inc., 7F, Bldg. C, Korea Bio Park, Daewangpangyo-ro 700, Bundang-gu, Seongnam City, Gyeonggi-do, Republic of Korea.

5. Department of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR.

6. School of Interdisciplinary Bioscience and Bioengineering, POSTECH, 77 Cheongam-ro, Hyogok-dong, Nam-gu, Pohang 37673, Republic of Korea.

7. Department of Mechanical Engineering, POSTECH, 77 Cheongam-ro, Hyogok-dong, Nam-gu, Pohang 37673, Republic of Korea.

8. Cell Death Disease Research Center, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Abstract

Priming human BM-MSCs with engineered HGF-MSCs in vivo significantly improves therapeutic potential for myocardial infarction.

Funder

National Research Foundation of Korea grants

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference25 articles.

1. Multilineage Potential of Adult Human Mesenchymal Stem Cells

2. Mesenchymal stem cells and cardiac repair

3. Manufacturing of primed mesenchymal stromal cells for therapy

4. Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010–2015)

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