A new algorithm to convert a normal antibody into the corresponding catalytic antibody-Reference-Cited by-同舟云学术

A new algorithm to convert a normal antibody into the corresponding catalytic antibody

Published:2020-03-27 Issue:13 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Hifumi Emi¹^ORCID,Taguchi Hiroaki²,Tsuda Haruna¹³,Minagawa Tetsuro¹³,Nonaka Tamami¹,Uda Taizo¹⁴^ORCID

Affiliation:

1. Oita University, Research Promotion Institute, 700 Dannoharu, Oita-shi, Oita 870-1192, Japan.

2. Suzuka University of Medical Science, Faculty of Pharmaceutical Sciences, 3500-3 Minamitamagaki-cho, Suzuka 510-0293, Japan.

3. Oita University, Department of Applied Chemistry, Faculty of Engineering, 700 Dannoharu, Oita-shi, Oita 870-1192, Japan.

4. Nanotechnology Laboratory, Institute of Systems, Information Technologies and Nanotechnologies (ISIT), 4-1 Kyudai-shinmachi, Fukuoka 879-5593, Japan.

Abstract

We report a system for converting a monoclonal antibody to the corresponding catalytic antibody by deletion of Pro 95 .

Funder

Ministry of Education, Culture, Sports, Science and Technology of Japan

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Catalytic Antibodies

2. Selective Chemical Catalysis by an Antibody

3. Catalytic Hydrolysis of Vasoactive Intestinal Peptide by Human Autoantibody

4. DNA Hydrolyzing Autoantibodies

5. Molecular cloning of a proteolytic antibody light chain.

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