Epitope-directed antibody selection by site-specific photocrosslinking-Reference-Cited by-同舟云学术

Epitope-directed antibody selection by site-specific photocrosslinking

Published:2020-04-03 Issue:14 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Chen Longxin¹²^ORCID,Zhu Chaoyang¹³^ORCID,Guo Hui¹^ORCID,Li Runting²^ORCID,Zhang Limeng²,Xing Zhenzhen²,Song Yue²,Zhang Zihan¹²,Wang Fuping¹,Liu Xiaofeng¹³,Zhang Yuhan¹,Ma Runlin Z.²³,Wang Feng¹^ORCID

Affiliation:

1. Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

2. Molecular Biology Laboratory, Zhengzhou Normal University, Zhengzhou 450044, China.

3. School of Life Sciences, The University of Chinese Academy of Sciences, Beijing 100049, China.

Abstract

We selected epitope-specific antibodies by cross-linking hits to the site-specific photocrosslinker on the target antigen.

Funder

National Key Research and Development Program of China Stem Cell and Translational Research

Chinese Academy of Sciences Pioneer Hundred Talents Program

the National Key R&D Program of China

Strategic Priority Research Program of CAS

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference42 articles.

1. The state-of-play and future of antibody therapeutics

2. The future of immune checkpoint therapy

3. Antibody Therapeutics in Cancer

4. Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platforms

5. Monoclonal antibodies: versatile platforms for cancer immunotherapy

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phage display for discovery of anticancer antibodies;New Biotechnology;2024-11

2. Facile Generation of Neutralizing Antibodies on Tyrosine Phosphorylated IRS1 by Epitope-Directed Elicitation;ACS Chemical Biology;2024-08-13

3. Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing;Communications Biology;2024-05-28

4. A general approach for selection of epitope-directed binders to proteins;Proceedings of the National Academy of Sciences;2024-04-29

5. Applications of genetic code expansion technology in eukaryotes;Protein & Cell;2023-10-17