Microglia control small vessel calcification via TREM2

Author:

Zarb Yvette12ORCID,Sridhar Sucheta12ORCID,Nassiri Sina3,Utz Sebastian Guido4ORCID,Schaffenrath Johanna12ORCID,Maheshwari Upasana12ORCID,Rushing Elisabeth J.5ORCID,Nilsson K. Peter R.6ORCID,Delorenzi Mauro37ORCID,Colonna Marco8ORCID,Greter Melanie4,Keller Annika12ORCID

Affiliation:

1. Department of Neurosurgery, Clinical Neurocentre, Zurich University Hospital, Zurich University, Zürich, Switzerland.

2. Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.

3. Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland.

4. Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

5. Institute of Neuropathology, Zurich University Hospital, Zurich, Switzerland.

6. Department of Chemistry, Linköping University, Linköping, Sweden.

7. Department of Oncology, University Lausanne, Lausanne, Switzerland.

8. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

Abstract

Microglial activity is needed to halt nascent vascular calcification.

Funder

Fondation Leducq

Swiss National Science Foundation

Krebsliga Schweiz

Horizon 2020

Schweizerische Herzstiftung

Fonds zur Förderung des akademischen Nachwuchses, University Zürich

Stiftung Synapsis - Alzheimer Forschung Schweiz AFS and Choupette Foundation

Forschungskredit und Stiftung für Forschung an der Medizinischen Fakultät der Universität Zürich

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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