Single-cell transcriptome analysis reveals cell lineage specification in temporal-spatial patterns in human cortical development

Author:

Fan Xiaoying123ORCID,Fu Yuanyuan4ORCID,Zhou Xin35ORCID,Sun Le35ORCID,Yang Ming16ORCID,Wang Mengdi5ORCID,Chen Ruiguo35ORCID,Wu Qian35ORCID,Yong Jun16ORCID,Dong Ji12ORCID,Wen Lu12ORCID,Qiao Jie1678ORCID,Wang Xiaoqun359ORCID,Tang Fuchou128ORCID

Affiliation:

1. Beijing Advanced Innovation Center for Genomics, Department of Obstetrics and Gynecology, College of Life Sciences, Third Hospital, Peking University, Beijing 100871, China.

2. Biomedical Pioneering Innovation Center and Center for Reproductive Medicine, Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing 100871, China.

3. State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Brain-Intelligence Science and Technology, Zhangjing Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

4. Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

5. University of Chinese Academy of Sciences, Beijing 100049, China.

6. Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China.

7. Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing 100191, China.

8. Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.

9. Advanced Innovation Center for Human Brain Protection, Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China.

Abstract

A single-cell survey of developing human CC was performed with comprehensive temporal and spatial information.

Funder

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China

National Key Research and Development Program of China Stem Cell and Translational Research

The Beijing Brin Initiative of Beijing Municipal Science & Technology Commission

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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