Attenuation of Dupuytren’s fibrosis via targeting of the STAT1 modulated IL-13Rα1 response-Reference-Cited by-同舟云学术

Attenuation of Dupuytren’s fibrosis via targeting of the STAT1 modulated IL-13Rα1 response

Published:2020-07-10 Issue:28 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Akbar Moeed¹^ORCID,Garcia-Melchor Emma¹,Chilaka Sabarinadh¹^ORCID,Little Kevin J.²,Sood Shatakshi¹,Reilly James H.¹,Liew Foo Y.¹³,McInnes Iain B.¹,Millar Neal L.¹^ORCID

Affiliation:

1. Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary and Life Sciences University of Glasgow, Glasgow, Scotland, UK.

2. Department of Orthopaedic Surgery, Queen Elizabeth University Hospital, Govan Road, Glasgow, Scotland, UK.

3. School of Biology and Basic Medical Sciences, Soochow University, Suzhou 215006, JS, China.

Abstract

Targeting STAT pathways may offer previously unidentified approaches in the management of fibrotic disorders.

Funder

Medical Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference58 articles.

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4. Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: Enhanced IL-13 production by IL-4–primed human mast cells

5. Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.

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