Esophageal extracellular matrix hydrogel mitigates metaplastic change in a dog model of Barrett’s esophagus-Reference-Cited by-同舟云学术

Esophageal extracellular matrix hydrogel mitigates metaplastic change in a dog model of Barrett’s esophagus

Published:2020-07-03 Issue:27 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Naranjo Juan Diego¹²^ORCID,Saldin Lindsey T.¹³^ORCID,Sobieski Eric¹,Quijano Lina M.¹^ORCID,Hill Ryan C.⁴^ORCID,Chan Patrick G.¹⁵,Torres Crisanto¹⁵,Dziki Jenna L.¹²,Cramer Madeline C.¹³^ORCID,Lee Yoojin C.¹³^ORCID,Das Rohit⁶,Bajwa Anant K.¹,Nossair Rania¹^ORCID,Klimak Molly¹,Marchal Lucile¹^ORCID,Patel Shil¹^ORCID,Velankar Sachin S.¹⁷^ORCID,Hansen Kirk C.⁴^ORCID,McGrath Kevin⁶,Badylak Stephen F.¹²³^ORCID

Affiliation:

1. McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.

2. Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.

3. Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.

4. Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

5. Department of Cardiothoracic Surgery, UPMC, Pittsburgh, PA 15213, USA.

6. Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, UPMC, Pittsburgh, PA 15213, USA.

7. Department of Chemical Engineering, Department of Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Abstract

Oral delivery of esophageal extracellular matrix hydrogel mitigates mucosal inflammation and metaplasia in a dog model of reflux.

Funder

Office of Naval Research

National Cancer Institute

Clinical and Translational Science Institute, University of Pittsburgh

BARD

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference60 articles.