Na + -dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters-Reference-Cited by-同舟云学术

Na + -dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters

Published:2020-11-20 Issue:47 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Alleva C.¹^ORCID,Kovalev K.¹²³⁴⁵^ORCID,Astashkin R.²⁴^ORCID,Berndt M. I.¹^ORCID,Baeken C.³⁶,Balandin T.³⁶^ORCID,Gordeliy V.²³⁴⁶,Fahlke Ch.¹⁴^ORCID,Machtens J.-P.¹⁷^ORCID

Affiliation:

1. Institute of Biological Information Processing (IBI-1), Molekular- und Zellphysiologie, and JARA-HPC, Forschungszentrum Jülich, Jülich, Germany.

2. Institut de Biologie Structurale (IBS), Université Grenoble Alpes-CEA-CNRS, 38000 Grenoble, France.

3. Institute of Biological Information Processing (IBI-7), Structural Biochemistry, Forschungszentrum Jülich, Jülich, Germany.

4. Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia.

5. Institute of Crystallography, RWTH Aachen University, Aachen, Germany.

6. JuStruct: Jülich Centre for Structural Biology, Forschungszentrum Jülich, Jülich, Germany.

7. Institute of Clinical Pharmacology, RWTH Aachen University, Aachen, Germany.

Abstract

Na + -dependent conformational changes ensure efficient secondary active glutamate uptake.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference60 articles.

1. Mechanisms of Glutamate Transport

2. Molecular and cellular physiology of sodium-dependent glutamate transporters

3. Flux coupling in a neuronal glutamate transporter

4. Na+:Aspartate Coupling Stoichiometry in the Glutamate Transporter Homologue GltPh

5. Stoichiometry of the Glial Glutamate Transporter GLT-1 Expressed Inducibly in a Chinese Hamster Ovary Cell Line Selected for Low Endogenous Na+-Dependent Glutamate Uptake

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