Skeletal muscle antagonizes antiviral CD8 + T cell exhaustion-Reference-Cited by-同舟云学术

Skeletal muscle antagonizes antiviral CD8 + T cell exhaustion

Published:2020-06-12 Issue:24 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Wu Jingxia¹^ORCID,Weisshaar Nina¹²,Hotz-Wagenblatt Agnes³^ORCID,Madi Alaa¹²,Ma Sicong¹,Mieg Alessa¹²,Hering Marvin¹,Mohr Kerstin¹,Schlimbach Tilo¹,Borgers Helena¹^ORCID,Cui Guoliang¹²^ORCID

Affiliation:

1. T Cell Metabolism Group (D140), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

2. Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany.

3. Core Facility Omics IT and Data Management, DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Abstract

Skeletal muscle shelters a group of T cells from systemic and chronic inflammation to protect T cell proliferative potential.

Funder

Helmholtz Association

Deutsche Forschungsgemeinschaft

Deutsche Krebshilfe

Rare Disease Foundation and BC Children’s Hospital Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference37 articles.

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5. An intermediate dose of LCMV clone 13 causes prolonged morbidity that is maintained by CD4+ T cells

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