M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery-Reference-Cited by-同舟云学术

M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery

Published:2021-03-12 Issue:11 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Li Zhiqi¹²^ORCID,Xiao Jun³^ORCID,Xu Xiaoyan³⁴^ORCID,Li Weiyun³⁵^ORCID,Zhong Ruiyue³^ORCID,Qi Linlin⁶⁷^ORCID,Chen Jiehui³,Cui Guizhong³^ORCID,Wang Shuang³^ORCID,Zheng Yuxiao³^ORCID,Qiu Ying³^ORCID,Li Sheng³^ORCID,Zhou Xin³⁸^ORCID,Lu Yao³^ORCID,Lyu Jiaying⁹,Zhou Bin³^ORCID,Zhou Jiawei¹⁰^ORCID,Jing Naihe³,Wei Bin⁶⁷⁸^ORCID,Hu Jin¹¹¹¹²^ORCID,Wang Hongyan²¹³^ORCID

Affiliation:

1. Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.

2. Neurosurgical Institute, Fudan University, Shanghai 200040 China.

3. State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

4. Experimental Immunology Branch, National Cancer Institute, U.S. National Institutes of Health, Bethesda, MD, USA.

5. School of Life Sciences, Xiamen University, Xiamen, Fujian, China.

6. School of Life Sciences, Shanghai University, Shanghai 200444, China.

7. Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.

8. Cancer Center, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai 200072, China.

9. Department of Biostatistics, School of Public Health, Fudan University, Shanghai, China.

10. Institute of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China.

11. Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.

12. Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.

13. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.

Abstract

The combination use of TGF-β, M-CSF, and IL-6 represents a promising therapy to repair traumatic brain injury.

Funder

National Natural Science Foundation of China

the Ministry of Science and Technology of China

The Strategic Priority Research Program of the Chinese Academy of Sciences

the Hundred Talents Program of the Chinese Academy of Sciences

the State Key Laboratory of Cell Biology, SIBCB, CAS

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference62 articles.

1. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

2. Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

3. Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

4. Alternative Activation of Macrophages: Mechanism and Functions

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