HEx: A heterologous expression platform for the discovery of fungal natural products-Reference-Cited by-同舟云学术

HEx: A heterologous expression platform for the discovery of fungal natural products

Published:2018-04-06 Issue:4 Volume:4 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Harvey Colin J. B.¹^ORCID,Tang Mancheng²^ORCID,Schlecht Ulrich¹,Horecka Joe¹,Fischer Curt R.¹³^ORCID,Lin Hsiao-Ching²,Li Jian¹^ORCID,Naughton Brian¹,Cherry James¹^ORCID,Miranda Molly¹,Li Yong Fuga¹,Chu Angela M.¹^ORCID,Hennessy James R.¹,Vandova Gergana A.¹,Inglis Diane⁴^ORCID,Aiyar Raeka S.¹^ORCID,Steinmetz Lars M.¹⁴⁵,Davis Ronald W.¹⁴^ORCID,Medema Marnix H.⁶^ORCID,Sattely Elizabeth⁷,Khosla Chaitan³⁷⁸,St. Onge Robert P.¹^ORCID,Tang Yi²⁹^ORCID,Hillenmeyer Maureen E.¹

Affiliation:

1. Stanford Genome Technology Center, Stanford University School of Medicine, Palo Alto, CA 94304, USA.

2. Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA.

3. Stanford ChEM-H (Chemistry, Engineering and Medicine for Human Health), Stanford University, Palo Alto, CA 94304, USA.

4. Department of Genetics, Stanford University School of Medicine, Palo Alto, CA 94304, USA.

5. European Molecular Biology Laboratory Heidelberg, 69117 Heidelberg, Germany.

6. Bioinformatics Group, Wageningen University, Wageningen, Netherlands.

7. Department of Chemical Engineering, Stanford University, Palo Alto, CA 94304, USA.

8. Department of Chemistry, Stanford University, Palo Alto, CA 94304, USA.

9. Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.

Abstract

We develop a novel synthetic biology platform for rapid, scalable expression of fungal biosynthetic genes and encoded metabolites.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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