Suprachoroidal gene transfer with nonviral nanoparticles-Reference-Cited by-同舟云学术

Suprachoroidal gene transfer with nonviral nanoparticles

Published:2020-07-03 Issue:27 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Shen Jikui¹^ORCID,Kim Jayoung²³^ORCID,Tzeng Stephany Y.²³^ORCID,Ding Kun¹^ORCID,Hafiz Zibran¹,Long Da¹,Wang Jiangxia⁴,Green Jordan J.¹²³⁵⁶^ORCID,Campochiaro Peter A.¹⁷^ORCID

Affiliation:

1. Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

2. Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

3. Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

4. Johns Hopkins Biostatistics Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

5. Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.

6. Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.

7. Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Abstract

Suprachoroidal gene transfer with nonviral nanoparticles provides noninvasive transgene expression in photoreceptors and RPE.

Funder

National Institutes of Health

National Eye Institute

Research to Prevent Blindness

James and Carole Free Catalyst Award

Barth Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference38 articles.

1. Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

2. Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

3. Treatment of Leber Congenital Amaurosis Due toRPE65Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial

4. Cloning of a gene that is rearranged in patients with choroideraemia

5. Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

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