Niche and local geography shape the pangenome of wastewater- and livestock-associated Enterobacteriaceae-Reference-Cited by-同舟云学术

Niche and local geography shape the pangenome of wastewater- and livestock-associated Enterobacteriaceae

Published:2021-04-09 Issue:15 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Shaw Liam P.¹^ORCID,Chau Kevin K.¹^ORCID,Kavanagh James¹^ORCID,AbuOun Manal²^ORCID,Stubberfield Emma²^ORCID,Gweon H. Soon³⁴^ORCID,Barker Leanne¹⁵,Rodger Gillian¹⁵^ORCID,Bowes Mike J.³^ORCID,Hubbard Alasdair T. M.¹⁶,Pickford Hayleah¹⁵,Swann Jeremy¹⁷^ORCID,Gilson Daniel⁸^ORCID,Smith Richard P.⁸,Hoosdally Sarah J.¹,Sebra Robert⁹¹⁰,Brett Howard¹¹^ORCID,Peto Tim E. A.¹⁵⁷,Bailey Mark J.³,Crook Derrick W.¹⁵⁷^ORCID,Read Daniel S.³^ORCID,Anjum Muna F.²,Walker A. Sarah¹⁵⁷^ORCID,Stoesser Nicole¹⁵^ORCID,

Affiliation:

1. Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.

2. Department of Bacteriology, Animal and Plant Health Agency (APHA), Woodham Lane, Addlestone, Surrey KT15 3NB, UK.

3. UK Centre for Ecology & Hydrology (UKCEH), Benson Lane, Crowmarsh Gifford, Wallingford OX10 8BB, UK.

4. School of Biological Sciences, University of Reading, Reading RG6 6AS, UK.

5. NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.

6. Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.

7. NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford OX4 9DU, UK.

8. Department of Epidemiological Sciences, The Animal and Plant Health Agency (APHA), Woodham Lane, Addlestone, Surrey KT15 3NB, UK.

9. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

10. Sema4, a Mount Sinai venture, 333 Ludlow Street, North Tower, 8th floor, Stamford, CT 06902, USA.

11. Thames Water Utilities, Clearwater Court, Vastern Road, Reading RG1 8DB, UK.

Abstract

The pangenome of Escherichia coli from nearby farms shows how livestock host and local geography shape bacterial populations.

Funder

Wellcome

NIHR Oxford Biomedical Research Centre

Antimicrobial Resistance Cross-council Initiative

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference69 articles.

1. Antimicrobial Resistance in Escherichia coli

2. EnvironmentalEscherichia coli: ecology and public health implications-a review

3. High genomic diversity of multi-drug resistant wastewater Escherichia coli

4. E. coli as an all-rounder: The thin line between commensalism and pathogenicity;Leimbach A.;Curr. Top. Microbiol. Immunol.,2013

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