How low can you go? Air pollution affects mortality at very low levels

Author:

Weichenthal Scott12ORCID,Pinault Lauren3,Christidis Tanya3ORCID,Burnett Richard T.4ORCID,Brook Jeffrey R.5,Chu Yen6,Crouse Dan L.7ORCID,Erickson Anders C.6ORCID,Hystad Perry8ORCID,Li Chi9ORCID,Martin Randall V.910ORCID,Meng Jun1011ORCID,Pappin Amanda J.2ORCID,Tjepkema Michael3,van Donkelaar Aaron910,Weagle Crystal L.9ORCID,Brauer Michael46ORCID

Affiliation:

1. McGill University, Montreal, QC, Canada.

2. Health Canada, Ottawa, ON, Canada.

3. Statistics Canada, Ottawa, ON, Canada.

4. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

5. University of Toronto, Toronto, ON, Canada.

6. University of British Columbia, Vancouver, BC, Canada.

7. Health Effects Institute, Boston, MA, USA.

8. Oregon State University, Corvallis, OR, USA.

9. Dalhousie University, Halifax, NS, Canada.

10. Washington University, Saint Louis, WA, USA.

11. Air Quality Research Division, Environment and Climate Change Canada, Toronto, ON, Canada.

Abstract

The World Health Organization (WHO) recently released new guidelines for outdoor fine particulate air pollution (PM 2.5 ) recommending an annual average concentration of 5 μg/m 3 . Yet, our understanding of the concentration-response relationship between outdoor PM 2.5 and mortality in this range of near-background concentrations remains incomplete. To address this uncertainty, we conducted a population-based cohort study of 7.1 million adults in one of the world’s lowest exposure environments. Our findings reveal a supralinear concentration-response relationship between outdoor PM 2.5 and mortality at very low (<5 μg/m 3 ) concentrations. Our updated global concentration-response function incorporating this new information suggests an additional 1.5 million deaths globally attributable to outdoor PM 2.5 annually compared to previous estimates. The global health benefits of meeting the new WHO guideline for outdoor PM 2.5 are greater than previously assumed and indicate a need for continued reductions in outdoor air pollution around the world.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference32 articles.

1. World Health Organization WHO Global Air Quality Guidelines: Particulate Matter (PM2.5 and PM10) Ozone Nitrogen Dioxide Sulfur Dioxide And Carbon Monoxide (World Health Organization 2021); https://apps.who.int/iris/handle/10665/345329 License: CC BY-NC-SA 3.0 IGO.

2. U.S. Environmental Protection Agency National Ambient Air Quality Standards (NAAQS) for PM (U.S. Environmental Protection Agency 2021); www.epa.gov/pm-pollution/national-ambient-air-quality-standards-naaqs-pm.

3. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

4. Air Pollution and Mortality in the Medicare Population

5. Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis

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