Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke

Author:

Sánchez-Morán Irene12ORCID,Rodríguez Cristina12ORCID,Lapresa Rebeca12ORCID,Agulla Jesús12ORCID,Sobrino Tomás3,Castillo José3ORCID,Bolaños Juan P.124ORCID,Almeida Angeles12ORCID

Affiliation:

1. Institute of Functional Biology and Genomics, CSIC, University of Salamanca, Calle Zacarías González 2, 37007 Salamanca, Spain.

2. Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Calle Zacarías González 2, 37007 Salamanca, Spain.

3. Clinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.

4. CIBERFES, Instituto de Salud Carlos III, Madrid, Spain.

Abstract

Ischemia-induced WRAP53 nuclear accumulation promotes DNA damage repair resulting in functional recovery after stroke.

Funder

Fundacion BBVA

Fundación Ramón Areces

European Commission

Instituto de Salud Carlos III

Ministerio de Ciencia e Innovación

Junta de Castilla y León

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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