Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin-Reference-Cited by-同舟云学术

Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin

Author:

Xu Cheng¹^ORCID,Shen Wei-Bin¹^ORCID,Reece E. Albert¹²,Hasuwa Hidetoshi³,Harman Christopher¹,Kaushal Sunjay⁴^ORCID,Yang Peixin¹²^ORCID

Affiliation:

1. Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.

2. Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, USA.

3. Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan.

4. Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.

Abstract

A microRNA-activated pathway in maternal diabetes–induced neuroepithelial cell senescence leads to neural tube defects.

Funder

National Institutes of Health

National Institute of Child Health and Human Development

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference60 articles.

1. Prevention of neural tube defects and proper folate periconceptional supplementation;Cavalli P.;J. Prenat. Med.,2008

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