DNA methylation at a nutritionally sensitive region of the PAX8 gene is associated with thyroid volume and function in Gambian children-Reference-Cited by-同舟云学术

DNA methylation at a nutritionally sensitive region of the PAX8 gene is associated with thyroid volume and function in Gambian children

Published:2021-11-05 Issue:45 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Candler Toby¹^ORCID,Kessler Noah J.²^ORCID,Gunasekara Chathura J.³,Ward Kate A.¹⁴,James Philip⁵^ORCID,Laritsky Eleonora³,Baker Maria S.³,Dyer Roger⁶^ORCID,Elango Rajavel⁶^ORCID,Jeffries David¹^ORCID,Waterland Robert A.³⁷^ORCID,Moore Sophie E.¹⁸^ORCID,Ludgate Marian⁹^ORCID,Prentice Andrew M.¹^ORCID,Silver Matt J.¹^ORCID

Affiliation:

1. MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine, London, UK.

2. Department of Genetics, University of Cambridge, Cambridge, UK.

3. USDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

4. MRC Lifecourse Epidemiology, University of Southampton, Southampton, UK.

5. Department of Population Health, London School of Hygiene and Tropical Medicine, London, UK.

6. British Columbia Children’s Hospital Research Institute, Vancouver, BC, Canada.

7. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

8. Department of Women and Children’s Health, King’s College London, London, UK.

9. Thyroid Research Group, School of Medicine, Cardiff University, Cardiff, UK.

Abstract

Child PAX8 methylation is associated with thyroid volume and function and influenced by maternal periconceptional nutrition.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference80 articles.

1. Thyroid hormone in health and disease

2. Thyroid Disorders in Children and Adolescents

3. A Review of the Clinical Consequences of Variation in Thyroid Function Within the Reference Range

4. Early pregnancy thyroid hormone reference ranges in Chilean women: the influence of body mass index

5. Paradoxical Relationship Between Body Mass Index and Thyroid Hormone Levels: A Study Using Mendelian Randomization

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