Primary cilia as the nexus of biophysical and hedgehog signaling at the tendon enthesis-Reference-Cited by-同舟云学术

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Primary cilia as the nexus of biophysical and hedgehog signaling at the tendon enthesis

Published:2020-10-30 Issue:44 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Fang Fei¹^ORCID,Schwartz Andrea G.²,Moore Emily R.³^ORCID,Sup McKenzie E.¹⁴,Thomopoulos Stavros¹⁴^ORCID

Affiliation:

1. Department of Orthopedic Surgery, Columbia University, New York, NY, 10032, USA.

2. Department of Orthopedic Surgery, Washington University in St. Louis, St. Louis, MO, 63130, USA.

3. School of Dental Medicine, Harvard University, Cambridge, MA, 02138, USA.

4. Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.

Abstract

Primary cilia at the tendon enthesis serve as mechanosensors and Hh signal transducers.

Funder

National Cancer Institute

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference49 articles.

1. Enthesitis: from pathophysiology to treatment

2. Targeting the NF-κB signaling pathway in chronic tendon disease

3. Tendon injury: from biology to tendon repair

4. Enthesis regeneration: A role for Gli1+ progenitor cells;Schwartz A. G.;Development,2017

5. Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment

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